Protein Purification
Aprotinin, Analytical Grade, MP Biomedicals™
Forms stable complexes with enzymes. Aprotinin, Analytical Grade, MP Biomedicals is a competitive serine proteinase inhibitor that works by blocking the active sites of enzymes. This binding is reversible with most aprotinin-protease complexes, dissociati
MilliporeSigma™ Calbiochem™ Menin-MLL Interaction Inhibitor, MI-2-2
A cell-permeable thienopyrimidine compound
MilliporeSigma™ Calbiochem™ Leupeptin, Hemisulfate, Synthetic
Synthetic version of the microbial-derived inhibitor Leupeptin against trypsin-like and cysteine protease activities.
Thermo Scientific Chemicals Leupeptin Hemisulfate
CAS: 103476-89-7 Molecular Formula: C20H39N6O4+
MilliporeSigma™ Calbiochem™ JNK Inhibitor II, Negative Control
The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Carboplatin
An analog of Cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.
MilliporeSigma™ Calbiochem™ Kenpaullone
A potent, cell-permeable, and reversible inhibitor of glycogen synthase kinase-3β (IC50 = 230 nM), Lck (IC50 = 470 nM), and cyclin-dependent kinases (Cdks).
MilliporeSigma™ Calbiochem™ AhR Antagonist
The AhR Antagonist, also referenced under CAS 301326-22-7, controls the biological activity of AhR.
MilliporeSigma™ Calbiochem™ Ro-20-1724
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ GPR40 Antagonist, GW1100
The GPR40 Antagonist, GW1100, also referenced under CAS 306974-70-9, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Resveratrol, Triacetyl
A cell-permeable triacetate resveratrol prodrug that is easily converted to resveratrol by esterase activity and exhibits similar bioactivity as resveratrol in cell cultures.
MilliporeSigma™ Calbiochem™ PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated
The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ JmjC Histone Demethylase Inhibitor, n-Octyl-IOX1
A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC50 = 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).
MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor VI, ICG-001
A cell-permeable pyrazinopyrimidinecarboxamide that competes against β-catenin for CBP (CREB-binding protein) binding and selectively prevents CBP- but not p300-, dependent TCF/β-catenin transcriptional regulations both in cultures in vitro (5 to 25μM) and in mice in vivo (5mg/kg/day via osmotic pump infusion), while not affecting CBP-dependent transcriptional activities mediated by the AP-1 or CRE c
MilliporeSigma™ Calbiochem™ SHP1/2 PTPase Inhibitor, NSC-87877
The SHP1/2 PTPase Inhibitor, NSC-87877, also referenced under CAS 56932-43-5, controls the biological activity of SHP1/2 PTPase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.